Wednesday, 12 March 2014 15:47

Anticoagulation news items. Week commencing 3rd March 2014

Describing deprescribing

Drug and Therapeutics Bulletin

This article discusses increasing multimorbidity and polypharmacy amongst the population and the risks associated with these factors. The article highlights that stopping prescribing or "deprescribing" is an important consideration in the medicines optimisation process.

 

Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial

The Lancet

Elastic compression stockings (ECS) did not prevent post-thrombotic syndrome after 1st proximal DVT [incidence of PTS=14.2% in active ECS vs 12.7% in placebo (adjusted HR 1.13, 95% CI 0.73-1.76; p=0.58)]. The authors state the findings do not support routine ECS use post DVT.

 

Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation

Journal of the American Medical Association

This cohort study (n=24,317) found that warfarin (vs. none) was linked to lower 1-year risk for composite of death, MI, and ischaemic stroke without higher risk of bleeding in consecutive acute MI patients with AF. This association was not related to severity of concurrent CKD.

 

The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service.
Further details on this service can be found at: http://www.evidence.nhs.uk/about-evidence-services/content-and-sources/medicines-information/new-medicines-awareness-services