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Monday, 25 August 2014 15:07

Anticoagulation news items. Week commencing 18th August 2014

PLATO study of ticagrelor for ACS gets all clear from US

The US Department of Justice has closed its investigation into the phase III PLATO trial which formed the basis for regulatory approval of ticagrelor (Brilique™ in UK) for acute coronary syndrome.


Hospital Performance for Pharmacologic Venous Thromboembolism Prophylaxis and Rate of Venous Thromboembolism: A Cohort Study

JAMA Internal Medicine
This US retrospective study found no statistically significant difference in VTE rates within 90 days of admission in medical patients between hospitals with low, moderate or high use of pharmacological VTE prophylaxis.


Revised SPCs: Xarelto (rivaroxaban) 10mg, 15mg and 20mg film-coated tablets

electronic Medicines Compendium

Information on converting from parenteral anticoagulants to rivaroxaban has been added to section 4.2 (posology and method of administration).



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: