Saturday, 13 September 2014 13:33

Anticoagulation news items. Week commencing 8th September 2014

The optimal management of anti-thrombotic therapy after valve replacement: certainties and uncertainties

European Heart Journal
This review summarises the current knowledge of the management of antithrombotic therapy after valve replacement, paying particular attention to persisting gaps in knowledge.


Patient self-testing and self-management of oral anticoagulation with vitamin K antagonists: guidance from the British Committee for Standards in Haematology

British Journal of Haematology
This guideline on the clinical effectiveness and health economics of patient self-testing and self-management of oral anticoagulant therapy updates a previous guideline published in 2005.


Measurement of non-Coumarin anticoagulants and their effects on tests of Haemostasis: Guidance from the British Committee for Standards in Haematology

British Journal of Haematology
This article provides guidance on the clinically important issues regarding the laboratory assessment of non-coumarin anticoagulants (new oral anticoagulants; heparins, bivalirudin; fondaparinux; argatroban; danaparoid) and their impact on laboratory tests of haemostasis.


Impact of sepsis on risk of postoperative arterial and venous thromboses: large prospective cohort study

British Medical Journal
This US study of patients undergoing inpatient or outpatient surgical procedures found that the presence of preoperative systemic inflammatory response syndrome or any sepsis was associated with an increased risk of an arterial or venous thrombosis post-surgery (odds ratio 3.1).


Interventions for treating acute bleeding episodes in people with acquired hemophilia A

Cochrane Database of Systematic Reviews
No randomised clinical trials of haemostatic therapies for acquired hemophilia A were found thus, no recommendations can be made on the optimal haemostatic therapies based on the highest quality of evidence.



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: