Saturday, 10 October 2015 08:40

Anticoagulation news items. Weeks commencing 5th October 2015

Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial

European Heart Journal

Although the relative benefits of ticagrelor were similar in patients with reduced renal function (eGFR<60mL/min), absolute benefits were higher as their risk of major adverse CV events was higher. There was however an excess of minor bleeding events.

 

Cardiovascular Management in Pregnancy: Antithrombotic Agents and Antiplatelet Agents

Circulation

This article reviews the use of anticoagulants and antiplatelets during pregnancy and highlights their clinical utility in conditions including VTE, thrombophilias, mechanical heart valves, APLS, pre-eclampsia, intrauterine growth restriction, and placental abruption.

 

 

The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at:
http://www.evidence.nhs.uk/about-evidence-services/content-and-sources/medicines-information/new-medicines-awareness-services