Friday, 29 April 2016 21:10

Anticoagulation news items. Weeks commencing 25th April 2016

Antithrombin for the prevention of intraventricular hemorrhage in very preterm infants

Cochrane Database of Systematic Reviews

Administration of antithrombin seems not to reduce incidence/severity of intraventricular haemorrhage in very preterm infants. Limited evidence is available on other clinically relevant outcomes. Given imprecision of estimate, this review cannot provide definitive answer.


Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair

Cochrane Database of Systematic Reviews

Moderate quality evidence suggests extended-duration anticoagulants to prevent VTE should be considered for people undergoing hip replacement surgery, although the benefit should be weighed against the increased risk of minor bleeding.


The left atrial appendage: from embryology to prevention of thromboembolism

European Heart Journal

This article describes the anatomy and function of the left atrial appendage (LAA) and current imaging tools for the identification of anatomical varieties. It also covers pathogenetic mechanisms of LAA thrombosis in AF patients, and examines the evidence on treatment strategies.


Insights from the NHS: the adoption of self monitoring coagulation status using point of care coagulometers (the CoaguChek XS system and the INRatio2 PT/INR monitor) for atrial fibrillation and heart valve disease

County Durham and Darlington NHS Foundation Trust

This shared learning guide presents a care pathway for the INR self-testing service, including the protocol for patient selection and training and the specification for the Health Call INR service, developed by clinicians working in the anticoagulation clinic.



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: