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Friday, 12 May 2017 20:40

Anticoagulation news items. Week commencing 8th May 2017

Integrated care in atrial fibrillation: a systematic review and meta-analysis


The results of this analysis suggest that use of an integrated model of care delivery in AF, with multidisciplinary team and community supports to ensure patient involvement in their management and decisions involving their care, is associated with enhanced patient outcomes.


Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data

British Medical Journal

Cohort review (446,763 individuals) found an increased risk for myocardial infarction with the use of several NSAIDs for 1-7 days; ibuprofen, HR 1.48 (95% CI 1.00 to 2.26), diclofenac 1.50 (1.06-2.04), naproxen 1.53 (1.07-2.33) and rofecoxib, 1.58 (1.07-2.17).


Pharmacovigilance Risk Assessment Committee (PRAC) review of factor VIII medicines

European Medicines Agency

This review has concluded that there is no clear and consistent evidence of difference in the incidence of inhibitor development between the plasma-derived and recombinant DNA technology-derived classes of factor VIII medicines.



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: