Sunday, 08 June 2014 10:14

Anticoagulation news items. Week commencing 2nd June 2014

Time to treatment with recombinant tissue plasminogen activator and outcome of stroke in clinical practice: retrospective analysis of hospital quality assurance data with comparison with results from randomised clinical trials

British Medical Journal
In this study (n=84,439), the effectiveness of thrombolytic therapy in clinical practice was comparable with that shown in clinical trials, with a clear association between time to treatment and functional outcome. Therapy >4.5 hrs was associated with an increase in mortality.


Chronic thromboembolic pulmonary hypertension

The Lancet Respiratory Medicine
This review looks at the diagnosis and treatment of chronic thromboembolic pulmonary hypertension, a debilitating and life-threatening complication of acute pulmonary embolism that results from persistent obstruction of pulmonary arteries and progressive vascular remodelling.



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: