Saturday, 25 October 2014 12:55

Anticoagulation news items. Week commencing 20th October 2014

Acute coronary syndrome - rivaroxaban [ID532]: consultation document

National Institute for Health and Care Excellence

DRAFT guidance recommends rivaroxaban as option, in combination with aspirin plus clopidogrel/aspirin alone, for preventing atherothrombotic events in people who have had an ACS with elevated cardiac biomarkers. Risk of bleeding should be assessed before treatment is started.


Chronic vitamin K antagonist therapy and bleeding risk in ST elevation myocardial infarction patients


In patients with STEMI treated with primary PCI, chronic use of vitamin K antagonist (VKA) was associated with an increased risk of in-hospital major bleed (17.0% v 10.1% in those not on VKA). In those on VKA, glycoprotein inhibitors were associated with increased bleeding risk.


New product: Nuwiq (human coagulation factor VIII, simoctocog alfa)

electronic Medicines Compendium

Nuwiq is licensed for the treatment and prophylaxis of bleeding in patients with haemophilia A (congenital factor VIII deficiency). Dose and duration depend on the severity of the factor VIII deficiency, location and extent of the bleeding and the patient's clinical condition.



The above records have been identified by UKMi and feature in the NICE Medicines Awareness Service. Further details on this service can be found at: